Posted on:August 13, 2025

Mechanical Engineer, Fluidics/Perfusion at Until

Until is hiring a Mechanical Engineer, Fluidics/Perfusion in San Francisco, CA, US. On-site. Pay: USD 120k-200k/yr.

About Until

Until is developing reversible cryopreservation technology to preserve donated human organs at subzero temperatures without ice formation, then rewarm them for transplantation. The company aims to solve the donor organ procurement and matching problem, and is working toward whole-body reversible cryopreservation as a longer-term goal.

Mechanical Engineer, Fluidics/Perfusion job description

Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.
 
To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.
 
We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.
 

About You

  • Track record of exceptional engineering abilities
  • Deep understanding of heat and mass transfer principles
  • Experience designing fluidic systems for perfusion/heat exchangers
  • High degree of autonomy across full engineering stack: electromechanical design and fabrication, control software, physical modeling
  • Desire to join a fast-paced, scrappy engineering team
  • Preferred Qualifications

  • 3+ years experience/graduate level in Mechanical Engineering, Physics, or equivalent
  • Experience with organ perfusion in a research or clinical context
  • Experience working in a startup
  • Benefits

  • Opportunity for outsized impact creating the future as an early team member
  • Generous medical, dental and vision insurance coverage for employees and their dependents
  • Flexible time off and paid holidays
  • Competitive compensation package, including salary and equity
  • Access to a 401(k) retirement savings plan
  • FSA and commuter benefits
  • Subsidized lunch daily
  • Apply now

    Applications go straight to Until. We never sit between you and the employer.

    Apply now ↗
    Get new startup jobs by email
    Pick what you want to hear about. The first email confirms your alert, then we only write when something new matches. You can unsubscribe from any email.
    1 of 15 categories
    How often

    Similar engineering jobs

    All engineering jobs →